ACEI的副作用就是咳嗽,长期服用可能导致肺癌的说法不无道理。ACEI are associated with a dry, persistent cough in 5%-35% of patients who take them. The mechanism of cough is likely multifactorial. ACE inhibitors prevent the breakdown of bradykinin and substance P, resulting in an accumulation of these protussive mediators in the respiratory tract.
加拿大专家联合将这些神药拉下神坛!